HCID 13759840, compound → HCID 58530505, compound

HRID 2400957Notes

Reaction equation

HRID 2400957 reaction equation
[N:1]1([N:7]2[C:11](=[O:12])[CH2:10][S:9][C:8]2=[O:13])[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[Cl:14][C:15]1[CH:32]=[CH:31][C:18]([CH2:19][N:20]2[C:28]3[C:23](=[CH:24][C:25]([CH:29]=O)=[CH:26][CH:27]=3)[CH:22]=[N:21]2)=[C:17]([C:33]([F:36])([F:35])[F:34])[CH:16]=1>>[Cl:14][C:15]1[CH:32]=[CH:31][C:18]([CH2:19][N:20]2[C:28]3[C:23](=[CH:24][C:25](/[CH:29]=[C:10]4/[C:11](=[O:12])[N:7]([N:1]5[CH2:6][CH2:5][O:4][CH2:3][CH2:2]5)[C:8](=[O:13])[S:9]/4)=[CH:26][CH:27]=3)[CH:22]=[N:21]2)=[C:17]([C:33]([F:34])([F:36])[F:35])[CH:16]=1

Participants

3

Reactant 2

HCID 13759840HCID 13759840, compoundHCID 866545471-(4-chloro-2-(trifluoromethyl)benzyl)-1H-indazole-5-carbaldehyde

Product 1

HCID 58530505HCID 58530505, compound

Procedure

(5Z)-5-({1-[4-Chloro-2-(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-3-morpholin-4-yl-1,3-thiazolidine-2,4-dione was prepared from 3-morpholin-4-yl-thiazolidine-2,4-dione and [4-chloro-2-(trifluoromethyl)benzyl]-1H-indazol-5-carbaldehyde (from Example 1) following General Procedure F.

Sources & evidence

ORD record
ord-138f5a5a1bf841e6a19eb2be12986e20
Source dataset
uspto-grants-2014_08
Patent number
US08796256B2

Reaction notes

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