HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanolamine → N-[(5Z)-5-({1-[4-Chloro-2-(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]methanesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanolamine | HCID 700 | — |
| Reactant | 1-(4-chloro-2-(trifluoromethyl)benzyl)-1H-indazole-5-carbaldehyde | HCID 86654547 | — |
| Reactant | N-(2,4-dioxothiazolidin-3-yl)methanesulfonamide | HCID 86659694 | — |
| Product | N-[(5Z)-5-({1-[4-Chloro-2-(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]methanesulfonamide | HCID 58530655 | — |
Reaction Steps
N-[(5Z)-5-({1-[4-Chloro-2-(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]methanesulfonamide was prepared from N-(2,4-dioxo-thiazolidin-3-yl)-methanesulfonamide (from Example 360) and [4-chloro-2-(trifluoromethyl)benzyl]-1H-indazol-5-carbaldehyde (from Example 1) following General Procedure E. The compound was made as an ethanolamine salt following General Procedure T.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08796256B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-bed315441aa8457489ea3356ef97e29c |
| Source note | uspto-grants-2014_08 |