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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2400963Generated: October 26, 2026

1-(4-Chloro-2-trifluoromethyl-benzyl)-3-methyl-1H-indazole-5-carbaldehyde → N-[(5Z)-5-({1-[4-Chloro-2-(trifluoromethyl)benzyl]-3-methyl-1H-indazol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]methanesulfonamide

https://huagongshe.com/reaction/2400963

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Chloro-2-trifluoromethyl-benzyl)-3-methyl-1H-indazole-5-carbaldehydeHCID 86654591—
ReactantN-(2,4-dioxothiazolidin-3-yl)methanesulfonamideHCID 86659694—
ProductN-[(5Z)-5-({1-[4-Chloro-2-(trifluoromethyl)benzyl]-3-methyl-1H-indazol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]methanesulfonamideHCID 58530794—

Reaction Steps

N-[(5Z)-5-({1-[4-Chloro-2-(trifluoromethyl)benzyl]-3-methyl-1H-indazol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]methanesulfonamide was prepared from N-(2,4-dioxothiazolidin-3-yl)methanesulfonamide (from Example 360) and 1-[4-chloro-2-(trifluoromethyl)benzyl]-3-methyl-1H-indazol-5-carbaldehyde (from Example 36) following General Procedure E.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08796256B2
Source datasetuspto-grants-2014_08
ORD IDord-ea5aeb00e7e7425facd7618d9b981fa3
Source noteuspto-grants-2014_08