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HRID 2400969作成日：2026年10月25日

Ethanolamine → N-[(5Z)-5-({1-[4-Chloro-2-(trifluoromethyl)benzyl]-3-fluoro-1H-indazol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]methanesulfonamide

https://huagongshe.com/reaction/2400969

反応式

関与物質

役割名称HCID仕込み量
反応物EthanolamineHCID 700—
反応物N-(2,4-dioxothiazolidin-3-yl)methanesulfonamideHCID 86659694—
反応物1-(4-chloro-2-trifluoromethyl-benzyl)-3-fluoro-1H-indazole-5-carbaldehydeHCID 86659699—
生成物N-[(5Z)-5-({1-[4-Chloro-2-(trifluoromethyl)benzyl]-3-fluoro-1H-indazol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]methanesulfonamideHCID 58530683—

反応手順

N-[(5Z)-5-({1-[4-Chloro-2-(trifluoromethyl)benzyl]-3-fluoro-1H-indazol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]methanesulfonamide was prepared from N-(2,4-dioxothiazolidin-3-yl)methanesulfonamide (from Example 360) and 1-[4-chloro-2-(trifluoromethyl)benzyl]-3-fluoro-1H-indazol-5-carbaldehyde following General Procedure F. The compound was converted to the corresponding ethanolamine salt following General Procedure T.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08796256B2
出典データセットuspto-grants-2014_08
ORD IDord-0b76ca15591c4ab3a0d6f7e983585f0c
出典メモuspto-grants-2014_08