4-Chloro-2-(trifluoromethyl)benzyl bromide → 3-Bromo-1-(4-chloro-2-trifluoromethylbenzyl)-1H-indazole-5-carbaldehyde

HRID 2401006Notes

Reaction equation

HRID 2401006 reaction equation
[Br:1][C:2]1[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([CH:11]=[O:12])[CH:9]=2)[NH:4][N:3]=1.[Cl:13][C:14]1[CH:21]=[CH:20][C:17]([CH2:18]Br)=[C:16]([C:22]([F:25])([F:24])[F:23])[CH:15]=1>>[Br:1][C:2]1[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([CH:11]=[O:12])[CH:9]=2)[N:4]([CH2:18][C:17]2[CH:20]=[CH:21][C:14]([Cl:13])=[CH:15][C:16]=2[C:22]([F:24])([F:23])[F:25])[N:3]=1

Participants

3

Reactant 2

HCID 34925974-Chloro-2-(trifluoromethyl)benzyl bromideHCID 178519375HCID 178519375, compound

Product 1

HCID 866597093-Bromo-1-(4-chloro-2-trifluoromethylbenzyl)-1H-indazole-5-carbaldehyde

Procedure

3-Bromo-1-(4-chloro-2-trifluoromethylbenzyl)-1H-indazole-5-carbaldehyde was prepared from 3-bromo-1H-indazole-5-carbaldehyde and 4-chloro-2-(trifluoromethyl)benzyl bromide following General Procedure A.

Sources & evidence

ORD record
ord-9f2f77f6be4e48a4b98b64e9c01e5802
Source dataset
uspto-grants-2014_08
Patent number
US08796256B2

Reaction notes

Loading…