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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2401023Generated: October 25, 2026

2,3-Dichloropyrazine → N-(3-chloropyrazin-2-yl)-2-(trifluoromethyl)benzenesulfonamide

https://huagongshe.com/reaction/2401023

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-DichloropyrazineHCID 78575—
Reactant2-(Trifluoromethyl)benzenesulfonamideHCID 2778018—
ProductN-(3-chloropyrazin-2-yl)-2-(trifluoromethyl)benzenesulfonamideHCID 5758606963%

Reaction Steps

Following the general method as outlined for Intermediate 2, starting from 2,3-dichloropyrazine and 2-(trifluoromethyl)benzenesulfonamide, the title compound was isolated, after evaporation and recrystallization, as a yellowish solid in 63% yield (97% purity by HPLC).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08796280B2
Source datasetuspto-grants-2014_08
ORD IDord-72f8f967d4ed45618f5e18c914d36c64
Source noteuspto-grants-2014_08