HuagongsheHuagongshe Chemistry Print Report · For research reference only
n-Methyl-4-(trifluoromethoxy)aniline → HCID 11959962, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | n-Methyl-4-(trifluoromethoxy)aniline | HCID 737351 | — |
| Reactant | 2-chloro-N-{3-[4-(chloromethyl)phenyl]pyrazin-2-yl}benzenesulfonamide | HCID 57444254 | — |
| Product | HCID 11959962 | HCID 11959962 | 72% |
Reaction Steps
Following the general methods as outlined in Example 1 (Method B), starting from 2-chloro-N-{3-[4-(chloromethyl)phenyl]pyrazin-2-yl}benzenesulfonamide (Intermediate 8), and N-methyl-4-(trifluoromethoxy)aniline, the title compound was isolated as a yellow solid in 72% yield (99% purity by HPLC).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08796280B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-4e976f5e50ef4ea0acae38eb6e57b1f1 |
| Source note | uspto-grants-2014_08 |