HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Dihydro-2H-1,4-benzoxazine → HCID 11960336, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Dihydro-2H-1,4-benzoxazine | HCID 585096 | — |
| Reactant | N-{3-[4-(chloromethyl)phenyl]pyrazin-2-yl}-2-(trifluoromethyl)benzenesulfonamide | HCID 57444250 | — |
| Product | HCID 11960336 | HCID 11960336 | 65% |
Reaction Steps
Following the general method as outlined in Example 1 (Method B), starting from N-{3-[4-(chloromethyl)phenyl]pyrazin-2-yl}-2-(trifluoromethyl)benzenesulfonamide (Intermediate 9), and 3,4-dihydro-2H-1,4-benzoxazine, the title compound was isolated as a yellow solid in 65% yield (97% purity by HPLC).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08796280B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-511e75329d3e4faa82c84adb49ee3d5b |
| Source note | uspto-grants-2014_08 |