HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-N-methylbenzenamine → HCID 57444241, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-N-methylbenzenamine | HCID 70272 | — |
| Reactant | N-{3-[4-(chloromethyl)phenyl]pyrazin-2-yl}-2-(trifluoromethyl)benzenesulfonamide | HCID 57444250 | — |
| Product | HCID 57444241 | HCID 57444241 | 72% |
Reaction Steps
Following the general method as outlined in Example 1 (Method B), starting from N-{3-[4-(chloromethyl)phenyl]pyrazin-2-yl}-2-(trifluoromethyl)benzenesulfonamide (Intermediate 9), and 4-chloro-N-methylaniline, the title compound was isolated as a yellow solid in 72% yield (94% purity by HPLC).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08796280B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-ba8d521b76fe4757bae58cf902ed34e7 |
| Source note | uspto-grants-2014_08 |