HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Methylamino)benzonitrile → HCID 11960451, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Methylamino)benzonitrile | HCID 10964551 | — |
| Reactant | 2-chloro-N-{3-[4-(chloromethyl)phenyl]pyrazin-2-yl}benzenesulfonamide | HCID 57444254 | — |
| Product | HCID 11960451 | HCID 11960451 | 52% |
Reaction Steps
Following the general method as outlined in Example 1 (Method B), starting from N-{3-[4-(chloromethyl)phenyl]pyrazin-2-yl}-2-(chloro) benzenesulfonamide (Intermediate 8), and 4-(N-methylamino)-benzonitrile, the title compound was isolated as a yellow solid in 52% yield (99% purity by HPLC).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08796280B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-371b58171a2b476c8d98b4798100293e |
| Source note | uspto-grants-2014_08 |