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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2401065Generated: October 30, 2026

6-Fluoroindole → HCID 11960453, compound

https://huagongshe.com/reaction/2401065

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-FluoroindoleHCID 351278—
ReactantN-{3-[4-(chloromethyl)phenyl]pyrazin-2-yl}-2-(trifluoromethyl)benzenesulfonamideHCID 57444250—
ProductHCID 11960453HCID 1196045377%

Reaction Steps

Following the general method as outlined in Example 1 (Method B), starting from N-{3-[4-(chloromethyl)phenyl]pyrazin-2-yl}-2-(trifluoromethyl)benzenesulfonamide (Intermediate 9), and 6-fluoro-1H-indole, the title compound was isolated as a yellow solid in 77% yield (97% purity by HPLC).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08796280B2
Source datasetuspto-grants-2014_08
ORD IDord-d06c79bdd70a450999daccbf5170b067
Source noteuspto-grants-2014_08