HCID 71280376, compound → Ammonia

Participants

Reaction Steps

The title compound was synthesized in essentially the same manner using the procedures as set forth in Step 2 of Example 1, by cyclizing 4-(tert-butyl-diphenyl-silanyloxy)-1-{2-[2-methyl-6-((2S,3′R)-2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-pyridin-3-ylamino]-ethyl}-cyclohexanecarboxylic acid ethyl ester (132 mg, 0.19 mmol) to obtain 89 mg (72% over two steps) of the title compound after flash column chromatography (5% 7N NH3 in MeOH/CH2Cl2).

Provenance & Evidence