Hydrochloric Acid → 2-[5-((2S,3'S)-2-Methyl-[1,3']bipyrrolidinyl-1'-yl)-pyrazin-2-yl]-2,8-diaza-spiro[4.5]decan-1-one

Participants

Reaction Steps

Hydrochloric acid in dioxane (0.5 mL) was added to 2-[5-((2S,3′S)-2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-pyrazin-2-yl]-1-oxo-2,8-diaza-spiro[4.5]decane-8-carboxylic acid tert-butyl ester (0.0185 g, 0.038 mmol) and stirred at room temperature for 3 hours. Reaction mixture was then concentrated under vacuum to afford 0.018 g (96%) of the title compound.

Provenance & Evidence