HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol, 2,2,2-trifluoro-, sodium salt (1:1) → 5-bromo-6-methoxy-2-(1H-pyrazol-1-yl)pyrimidin-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol, 2,2,2-trifluoro-, sodium salt (1:1) | HCID 23677971 | — |
| Reactant | 5-bromo-6-chloro-2-(1H-pyrazol-1-yl)pyrimidin-4-amine | HCID 86677017 | — |
| Solvent | 2,2,2-Trifluoroethanol | HCID 6409 | — |
| Product | 5-bromo-6-methoxy-2-(1H-pyrazol-1-yl)pyrimidin-4-amine | HCID 57407238 | — |
Reaction Steps
The following example was synthesized using the procedure described for Example 43 from Intermediate 5 using a solution of sodium 2,2,2-trifluoroethanolate in 2,2,2-trifluoroethanol:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08796284B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-d8b3561c34794839b93bbd67d0e0df76 |
| Source note | uspto-grants-2014_08 |