HCID 86666718, compound → HCID 88438946, compound

HRID 2401362Notes

Reaction equation

HRID 2401362 reaction equation
ClC1C=CC(C(C2C=CC=CC=2C2C(C)=NOC=2/C=[N:20]/[S@@:21]([C:23]([CH3:26])([CH3:25])[CH3:24])=[O:22])=O)=CC=1.[Cl:30][C:31]1[CH:52]=[CH:51][C:34]([C:35]([C:37]2[CH:42]=[CH:41][CH:40]=[CH:39][C:38]=2[C:43]2[C:44]([CH:49]=O)=[N:45][O:46][C:47]=2[CH3:48])=[O:36])=[CH:33][CH:32]=1>>[Cl:30][C:31]1[CH:52]=[CH:51][C:34]([C:35]([C:37]2[CH:42]=[CH:41][CH:40]=[CH:39][C:38]=2[C:43]2[C:44](/[CH:49]=[N:20]/[S@@:21]([C:23]([CH3:26])([CH3:25])[CH3:24])=[O:22])=[N:45][O:46][C:47]=2[CH3:48])=[O:36])=[CH:33][CH:32]=1

Participants

3

Reactant 2

HCID 86666718HCID 86666718, compoundHCID 88439250HCID 88439250, compound

Product 1

HCID 88438946HCID 88438946, compound

Procedure

This material can be made in a similar manner as (R,E)-N-((4-(2-(4-chlorobenzoyl)phenyl)-3-methylisoxazol-5-yl)methylene)-2-methylpropane-2-sulfinamide starting from 4-(2-(4-chlorobenzoyl)phenyl)-5-methylisoxazole-3-carbaldehyde (1.10 g, 3.38 mmol). LC/MS m/z 429 [M+H]+.

Sources & evidence

ORD record
ord-5b83cac9a36945c5ba2fdb8ffefd4556
Source dataset
uspto-grants-2014_08
Patent number
US08796261B2

Reaction notes

Loading…