HuagongsheHuagongshe Chemistry Print Report · For research reference only
Azide → HCID 67814096, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Azide | HCID 33558 | — |
| Reactant | HCID 67813173 | HCID 67813173 | — |
| Reactant | HCID 67814531 | HCID 67814531 | — |
| Reactant | HCID 67951267 | HCID 67951267 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 67814096 | HCID 67814096 | — |
Reaction Steps
A reaction sequence similar to that used to prepare Compound 191 was followed, except that methyl 2-(5-(hydroxymethyl)-3-methylisoxazol-4-yl)-6-methoxynicotinate was used as starting material instead of (4-chlorophenyl)(2-(3-(hydroxymethyl)-5-methylisoxazol-4-yl)phenyl)methanone and methanol was used as the co-solvent for the conversion of the azide to the lactam. LC/MS m/z 246 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08796261B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-7270b2375dab47529dfb8b263f3ff881 |
| Source note | uspto-grants-2014_08 |