4-(N-Boc-amino)piperidine → HCID 57899177, 화합물

반응식

Cl[C:2]1[N:10]=[CH:9][N:8]=[C:7]2[C:3]=1[NH:4][C:5](=[O:11])[NH:6]2.[C:12]([O:16][C:17](=[O:25])[NH:18][CH:19]1[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]1)([CH3:15])([CH3:14])[CH3:13]>>[C:12]([O:16][C:17](=[O:25])[NH:18][CH:19]1[CH2:24][CH2:23][N:22]([C:2]2[N:10]=[CH:9][N:8]=[C:7]3[C:3]=2[NH:4][C:5](=[O:11])[NH:6]3)[CH2:21][CH2:20]1)([CH3:15])([CH3:13])[CH3:14]

참가 물질

반응물 2

HCID 7238334-(N-Boc-amino)piperidine

HCID 576592036-chloro-8,9-dihydro-7H-purin-8-one

생성물 1

HCID 57899177HCID 57899177, 화합물

실험 절차

By reacting 6-chloro-7,9-dihydro-purin-8-one with piperidin-4-yl-carbamic acid tert-butyl ester according to the method of Example 4A, the title compound was obtained. LC/MS: (LCT) Rt 5.68 [M+H]+ 335.

출처 및 근거

ORD 기록: ord-a16f3d1303834540832f0692f65345b0
출처 데이터셋: uspto-grants-2014_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08796293B2

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