Acetic Anhydride → HCID 57429031, compound

Participants

Reaction Steps

To a solution of (R)-1-(4-Benzyloxy-3-nitro-phenyl)-2-[benzyl-(2,5,6-trimethyl-indan-2-yl)-amino]-ethanol in pyridine is added acetic anhydride and the mixture stirred for 18 hours. The reaction mixture is quenched with water and after addition of ethyl acetate washed twice with aqueous KHSO4 solution, twice with aqueous NaHCO3 and once with brine. The product is purified by chromatoghaphy (silica, ethyl acetate/hexane 1:4). ES+ MS m/e 579 (MH+)

Provenance & Evidence