Benzyl(5,6-diethyl-2-methyl-indan-2-yl)-amine → 5,6-Diethyl-2-methyl-indan-2-ylamine

HRID 2401618Notes

Reaction equation

HRID 2401618 reaction equation
C([NH:8][C:9]1([CH3:22])[CH2:17][C:16]2[C:11](=[CH:12][C:13]([CH2:20][CH3:21])=[C:14]([CH2:18][CH3:19])[CH:15]=2)[CH2:10]1)C1C=CC=CC=1>CO.[Pd]>[CH2:18]([C:14]1[CH:15]=[C:16]2[C:11](=[CH:12][C:13]=1[CH2:20][CH3:21])[CH2:10][C:9]([NH2:8])([CH3:22])[CH2:17]2)[CH3:19]

Participants

4

Reactant 1

HCID 22499185Benzyl(5,6-diethyl-2-methyl-indan-2-yl)-amine

Product 1

HCID 224992325,6-Diethyl-2-methyl-indan-2-ylamine

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A solution of benzyl-(5,6-diethyl-2-methyl-indan-2-yl)-amine (0.48 g) in methanol (10 ml) is stirred under an atmosphere of hydrogen in the presence of 10% Pd/C at room temperature for 18 hours. The mixture is filtered through celite and the filtrate is concentrated in vacuo to give the title compound. ES+ MS m/e 204 (MH+)

Workup

  1. filtrationThe mixture is filtered through celite
  2. concentrationthe filtrate is concentrated in vacuo

Sources & evidence

ORD record
ord-e72a8c0feadc4732a3bb254a68f40760
Source dataset
uspto-grants-2014_08
Patent number
US08796307B2

Reaction notes

Loading…