Water → HCID 74222693, compound

Participants

Reaction Steps

50 mg of methyl 8-[({8-[(2,6-difluorobenzyl)oxy]-2-methylimidazo[1,2-a]pyridin-3-yl}carbonyl)-amino]octanoate Example 15 (0.11 mmol, 1 equivalent) were reacted with 0.5 ml of 1 M lithium hydroxide solution in water (0.53 mmol, 5 equivalents) analogously to Example 20 and worked up. This gave 25 mg (47% of theory; purity: 92%) of the title compound.

Provenance & Evidence