HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 240202Generated: October 30, 2026
2,2-Dimethyl-1,3-dioxane-4,6-dione → HCID 21883483, compound
https://huagongshe.com/reaction/240202
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2,2-Dimethyl-1,3-dioxane-4,6-dione | HCID 16249 | — |
| Reactant | 2-Aminobenzaldehyde | HCID 68255 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 21883483 | HCID 21883483 | 71.3% |
Reaction Steps
2-Aminobenzaldehyde (84.1 mg, 0.69 mmol) and Meldrum's acid (100 mg, 0.69 mmol) were combined in H2O (1 mL). The solution was stirred at 75° C. for 2 h. After cooling to room temperature, the precipitate was filtered and dried at suction to give 86.2 mg of 1,2-dihydro-quinoline-3-carboxylic acid with a yield of 66%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08642788B2 |
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| Source dataset | uspto-grants-2014_02 |
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| ORD ID | ord-5ef52b34e05c4e4fa46203c4166b41d0 |
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| Source note | uspto-grants-2014_02 |
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