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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 240202Generated: October 30, 2026

2,2-Dimethyl-1,3-dioxane-4,6-dione → HCID 21883483, compound

https://huagongshe.com/reaction/240202

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2-Dimethyl-1,3-dioxane-4,6-dioneHCID 16249—
Reactant2-AminobenzaldehydeHCID 68255—
SolventWaterHCID 962—
ProductHCID 21883483HCID 2188348371.3%

Reaction Conditions

Temperature75 °C

Reaction Steps

2-Aminobenzaldehyde (84.1 mg, 0.69 mmol) and Meldrum's acid (100 mg, 0.69 mmol) were combined in H2O (1 mL). The solution was stirred at 75° C. for 2 h. After cooling to room temperature, the precipitate was filtered and dried at suction to give 86.2 mg of 1,2-dihydro-quinoline-3-carboxylic acid with a yield of 66%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08642788B2
Source datasetuspto-grants-2014_02
ORD IDord-5ef52b34e05c4e4fa46203c4166b41d0
Source noteuspto-grants-2014_02