HCID 73453867, compound → HCID 18618665, compound

HRID 2402424Notes

Reaction equation

HRID 2402424 reaction equation
[OH:1][NH:2][C:3](=[O:21])[CH2:4][CH2:5][C:6]1[CH:11]=[CH:10][C:9]([CH:12]=[CH:13][CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[CH:8][CH:7]=1.ONC(=O)CCC1C=CC(CC=CC2C=CC=CC=2)=CC=1.C1(CC=CC2C=CC(C(O)=O)=CC=2)C=CC=CC=1.C1(C=CCC2C=CC(C(O)=O)=CC=2)C=CC=CC=1>>[OH:1][NH:2][C:3](=[O:21])[CH2:4][CH2:5][C:6]1[CH:11]=[CH:10][C:9]([CH2:12][CH2:13][CH2:14][C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=2)=[CH:8][CH:7]=1

Participants

4

Reactant 3

HCID 73453867HCID 73453867, compoundHCID 73453869HCID 73453869, compoundHCID 86620892HCID 86620892, compound

Product 1

HCID 18618665HCID 18618665, compoundYield 99%

Procedure

Following a procedure analogous to that described in Example 24, step 2, but substituting the mixture of N-hydroxy-3-[4-(3-phenyl-1-propenyl)-phenyl]-propanamide and N-hydroxy-3-[4-(3-phenyl-2-propenyl)-phenyl]-propanamide (155 mg, 0.55 mmol) for olefins 54, 155.4 mg (99%) of the title compound was obtained.

Sources & evidence

ORD record
ord-700466543b3b4a6b90226d26902f6123
Source dataset
uspto-grants-2014_08
Patent number
US08796330B2

Reaction notes

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