Cyclopropanecarboxaldehyde → HCID 178518685, compound

HRID 2402584Notes

Reaction equation

HRID 2402584 reaction equation
[CH:1]1([CH:4]=O)[CH2:3][CH2:2]1.[NH2:6][C@@H:7]1[CH2:12][CH2:11][C@H:10]([O:13][C:14]2[CH:15]=[C:16]3[C:21](=[CH:22][CH:23]=2)[C:20](=[O:24])[NH:19][CH:18]=[CH:17]3)[CH2:9][CH2:8]1>>[CH:1]1([CH2:4][NH:6][C@@H:7]2[CH2:8][CH2:9][C@H:10]([O:13][C:14]3[CH:15]=[C:16]4[C:21](=[CH:22][CH:23]=3)[C:20](=[O:24])[NH:19][CH:18]=[CH:17]4)[CH2:11][CH2:12]2)[CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 123114CyclopropanecarboxaldehydeHCID 178511695HCID 178511695, compound

Product 1

HCID 178518685HCID 178518685, compound

Procedure

125 was obtained as hydrochloride using the previously described general method employing cyclopropane carbaldehyde and cis-6-(4-amino-cyclohexyloxy)-2H-isoquinolin-1-one (28) as starting materials. Rt=1.04 min (Method B). Detected mass: 313.2 (M+H+).

Sources & evidence

ORD record
ord-88137ad21ae44abc88fe886bc0a83b20
Source dataset
uspto-grants-2014_08
Patent number
US08796458B2

Reaction notes

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