2,2,2-Trifluoro-N-(4-hydroxycyclohexyl)-N-methylacetamide → HCID 178484843, compound

Participants

Reaction Steps

2 g of 2,2,2-trifluoro-N-(4-hydroxy-cyclohexyl)-N-methyl-acetamide (149) were suspended in 10 mL of 1N HCl and heated in a microwave at 150° until conversion was complete. The resulting solution was lyophilized and the residue was taken up in water and lyophilized again, twice to yield 1.45 g of 4-methylamino-cyclohexanol (150). Rt=0.13 min (Method C). Detected mass: 130.3 (M+H+).

Provenance & Evidence