Skatole → 3-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

HRID 2402677Notes

Reaction equation

HRID 2402677 reaction equation
Cl[C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[NH:9][C:8]([B:11]1[O:15][C:14]([CH3:17])([CH3:16])[C:13]([CH3:19])([CH3:18])[O:12]1)=[CH:7]2.[CH3:20]C1C2C(=CC=CC=2)NC=1>>[CH3:20][C:7]1[C:6]2[C:10](=[CH:2][CH:3]=[CH:4][CH:5]=2)[NH:9][C:8]=1[B:11]1[O:15][C:14]([CH3:17])([CH3:16])[C:13]([CH3:19])([CH3:18])[O:12]1

Participants

3

Reactant 2

HCID 6736SkatoleHCID 532172117-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-1H-indole

Product 1

HCID 591331593-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

Procedure

Prepared according to a procedure analogous to that described for 7-chloro-2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indole using 3-methyl-1H-indole.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-fecb89b847fc4800b06046364c6745ef
Source dataset
uspto-grants-2014_08
Patent number
US08796455B2

Reaction notes

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