Potassium Carbonate → HCID 67308753, compound

Participants

Reaction Conditions

Reaction Steps

3-Hydroxy-benzoic acid tert-butyl ester (1.79 g) was dissolved in MeCN 75 ml, then bromo-hexadecanoic acid methyl ester (3.22 g) was added followed by K2CO3 (2.5 g). The reaction was stirred for 3 d at 80° C. The reaction mixture was filtered. The filtrate was evaporated, and the residue was dissolved in EtOAc 100 ml, and the EtOAc layer was washed twice with 100 ml brine. The organic layer was dried over MgSO4 filtered and the solvent was removed by evaporation to give 4.165 g (98%).

Provenance & Evidence