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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 240306Generated: October 25, 2026

Methanol → 3-methoxy-9-oxo-9H-indeno[1,2-b]pyrazine-2-carbonitrile

https://huagongshe.com/reaction/240306

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
Reactant9-oxo-9H-indeno(1,2-b)pyrazine-2,3-dicarbonitrileHCID 292929—
Product3-methoxy-9-oxo-9H-indeno[1,2-b]pyrazine-2-carbonitrileHCID 16065353126.5%

Reaction Steps

To a suspension of 1 (1.10 g, 4.7 mmol) in MeOH (47 ml) sodium (110 mg) was added and the mixture was stirred at room temperature for 16 hours. The precipitate was filtered, washed with EtOH and dried under vacuum, yielding 3 (1.03 g, 93%) as yellow-green solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08648076B2
Source datasetuspto-grants-2014_02
ORD IDord-b40012b19977406f87d5a10b4b6e4989
Source noteuspto-grants-2014_02