Itaconic acid → HCID 86671901, compound

Participants

Reaction Steps

Two hollow fiber modules (4×13, LiquiCell X40, Membrana) were assembled such that 3 continuous loops could be operated: (1) itaconic acid solution (2) solvent system (3) stripping solution. An itaconic acid solution (2 L, 60.0 g/L acid, pH 2.2) was circulated through the shell side of module 1. The ternary organic solvent system (20% TOA, 20% octanol, heptane) was circulated through the lumen of both modules. Lastly, aqueous sodium hydroxide (0.46 M) was circulated shell side of module 2. The volume ratios were 1:1:1. The three loops were run at 0.5 L/min. The simultaneous extraction and stripping were monitored for IA concentration and pH. In 7 hours 63% was recovered (5.4 g/L-hr) and the pH dropped to 4.7. The run was allowed to proceed overnight (25 hours total) resulting in an overall 78% recovery in the form of monosodium itaconate from the fermentation broth.

Provenance & Evidence