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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2403156Generated: November 1, 2026

Cyclohexylamine → Methyl 1-cyclohexylazetidine-2-carboxylate

https://huagongshe.com/reaction/2403156

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclohexylamineHCID 7965—
ReactantMethyl 2,4-dibromobutanoateHCID 296716—
ProductMethyl 1-cyclohexylazetidine-2-carboxylateHCID 353228676%

Reaction Steps

The reaction of methyl 2,4-dibromobutanoate 17 with cyclohexylamine 18A yielded methyl 1-(cyclohexyl)azetidine-2-carboxylate as a brown oil (76%). MS ISP (m/e): 198.2 (100) [(M+H)]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08802665B2
Source datasetuspto-grants-2014_08
ORD IDord-64ed877167954691aabfbe06c3d69b1f
Source noteuspto-grants-2014_08