HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S,4R)-4-(2-chlorophenylsulfonyl)-N-(1-cyanocyclopropyl)pyrrolidine-2-carboxamide → HCID 71711974, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S,4R)-4-(2-chlorophenylsulfonyl)-N-(1-cyanocyclopropyl)pyrrolidine-2-carboxamide | HCID 46946413 | — |
| Reactant | HCID 86692771 | HCID 86692771 | — |
| Product | HCID 71711974 | HCID 71711974 | — |
Reaction Steps
The reaction of (2S,4R)-4-(2-chlorophenylsulfonyl)-N-(1-cyanocyclopropyl)pyrrolidine-2-carboxamide 7H and lithium 1-(2,2-dimethyltetrahydro-2H-pyran-4-yl)azetidine-2-carboxylate 20H carried out according to the general procedure L yielded (2S,4R)-4-(2-chlorophenylsulfonyl)-N-(1-cyanocyclopropyl)-1-(1-(2,2-dimethyltetrahydro-2H-pyran-4-yl)azetidine-2-carbonyl)pyrrolidine-2-carboxamide 1:1 epimers as an off-white solid (quant.). MS ISP (m/e): 549.3 (100) [(M+H)]]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08802665B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-54d73f70890545e098594e8aa748842d |
| Source note | uspto-grants-2014_08 |