HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S,4R)-4-(2-chlorophenylsulfonyl)-N-(1-cyanocyclopropyl)pyrrolidine-2-carboxamide → HCID 71711170, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S,4R)-4-(2-chlorophenylsulfonyl)-N-(1-cyanocyclopropyl)pyrrolidine-2-carboxamide | HCID 46946413 | — |
| Reactant | HCID 68761060 | HCID 68761060 | — |
| Product | HCID 71711170 | HCID 71711170 | 91% |
Reaction Steps
The reaction of (2S,4R)-4-(2-chlorophenylsulfonyl)-N-(1-cyanocyclopropyl)pyrrolidine-2-carboxamide 7H with 1-(4-(tert-butoxycarbonyl)piperazin-1-yl)cyclopropanecarboxylic acid 16E carried out according to the general procedure L yielded tert-butyl 4-(1-((2S,4R)-4-(2-chlorophenylsulfonyl)-2-(1-cyanocyclopropylcarbamoyl)pyrrolidine-1-carbonyl)cyclopropyl)piperazine-1-carboxylate as a white solid (91%). MS ISN (m/e): 604.4/606.3 (41/15) [(M−H)]−, 664.3/666.4 (100/54) [(M+OAc)]−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08802665B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-81f2d99bca6a438fa99c761e5d85f924 |
| Source note | uspto-grants-2014_08 |