HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S,4R)-4-(2-chlorophenylsulfonyl)-N-(1-cyanocyclopropyl)pyrrolidine-2-carboxamide → HCID 71711295, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S,4R)-4-(2-chlorophenylsulfonyl)-N-(1-cyanocyclopropyl)pyrrolidine-2-carboxamide | HCID 46946413 | — |
| Reactant | HCID 86692793 | HCID 86692793 | — |
| Product | HCID 71711295 | HCID 71711295 | 52% |
Reaction Steps
The reaction of (2S,4R)-4-(2-chlorophenylsulfonyl)-N-(1-cyanocyclopropyl)pyrrolidine-2-carboxamide 7H with 1-(4-phenylpiperidin-1-yl)cyclopropanecarboxylic acid hydrochloride 16H carried out according to the general procedure L yielded (2S,4R)-4-(2-chlorophenylsulfonyl)-N-(1-cyanocyclopropyl)-1-(1-(4-phenylpiperidin-1-yl)cyclopropanecarbonyl)pyrrolidine-2-carboxamide as an off-white solid (52%). MS ISP (m/e): 581.2 (100) [(M+H)]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08802665B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-4303cb9a0e524b16b5d18a538d39f2a8 |
| Source note | uspto-grants-2014_08 |