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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2403207Generated: October 31, 2026

(2S,4R)-4-(2-chlorophenylsulfonyl)-N-(1-cyanocyclopropyl)pyrrolidine-2-carboxamide → HCID 71711296, compound

https://huagongshe.com/reaction/2403207

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S,4R)-4-(2-chlorophenylsulfonyl)-N-(1-cyanocyclopropyl)pyrrolidine-2-carboxamideHCID 46946413—
ReactantHCID 86692794HCID 86692794—
ProductHCID 71711296HCID 7171129639%

Reaction Steps

The reaction of (2S,4R)-4-(2-chlorophenylsulfonyl)-N-(1-cyanocyclopropyl)pyrrolidine-2-carboxamide 7H with 1-(4-methylpiperidin-1-yl)cyclopropanecarboxylic acid hydrochloride 16I carried out according to the general procedure L yielded (2S,4R)-4-(2-chlorophenylsulfonyl)-N-(1-cyanocyclopropyl)-1-(1-(4-methylpiperidin-1-yl)cyclopropanecarbonyl)pyrrolidine-2-carboxamide as an off-white solid (39%). MS ISP (m/e): 519.2 (100) [(M+H)]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08802665B2
Source datasetuspto-grants-2014_08
ORD IDord-eb24c77d0a9b4ed7a3ec35194bf6e99e
Source noteuspto-grants-2014_08