HRID2403215

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：N#CC1(NC(=O)[C@@H]2C[C@@H](S(=O)(=O)c3ccc(Cl)cc3)CN2)CC1

HCID86692785

未命名化合物

HCID86692787

未命名化合物

PRODUCTS

生成物

结构：N#CC1(NC(=O)[C@@H]2C[C@@H](S(=O)(=O)c3ccc(Cl)cc3)CN2C(=O)C2(N3CCCCC3)CC2)CC1

HCID71711417

未命名化合物

收率 46%

PROCEDURE

实验过程

The reaction of (2S,4R)-4-(4-chlorophenylsulfonyl)-N-(1-cyanocyclopropyl)pyrrolidine-2-carboxamide 7B with 1-(piperidin-1-yl)cyclopropanecarboxylic acid hydrochloride 16A carried out according to the general procedure L yielded (2S,4R)-4-(4-chlorophenylsulfonyl)-N-(1-cyanocyclopropyl)-1-(1-(piperidin-1-yl)cyclopropanecarbonyl)pyrrolidine-2-carboxamide as a light yellow viscous oil (46%). MS ISP (m/e): 505.2/507.2 [(M+H)]+.