HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Formylphenylboronic acid → HCID 86619250, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Formylphenylboronic acid | HCID 2734356 | — |
| Reactant | 4-(2-Chloro-6-((4-methylpiperazin-1-yl)methyl)thieno[3,2-d]pyrimidin-4-yl)morpholine | HCID 57420338 | — |
| Product | HCID 86619250 | HCID 86619250 | — |
Reaction Steps
2-Chloro-6-(4-methyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine was reacted with 3-formyl phenyl boronic acid in General Procedure A. Purification on silica yielded 3-[6-(4-methyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-2-yl]-benzaldehyde. This was then treated with sodium borohydride in methanol to give the desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08802670B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-02208028810249139cbf454a45f3abc4 |
| Source note | uspto-grants-2014_08 |