1-Methyl-4-(methylamino)piperidine → (2-Chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-methyl-(1-methyl-piperidin-4-yl)-amine

Participants

Role	Name	HCID	Charge
Reactant	1-Methyl-4-(methylamino)piperidine	HCID 566323	—
Reactant	2-Chloro-4-morpholinothieno[3,2-d]pyrimidine-6-carbaldehyde	HCID 45789985	—
Product	(2-Chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-methyl-(1-methyl-piperidin-4-yl)-amine	HCID 86619251	—

Reaction Steps

Reaction between 2-chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidine-6-carbaldehyde and 1-methyl-4-(methylamino)piperidine using procedure C yielded (2-chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-methyl-(1-methyl-piperidin-4-yl)-amine. This compound was subjected to procedure A to yield the desired final compound which was purified using flash chromatography.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08802670B2
Source dataset	uspto-grants-2014_08
ORD ID	ord-da0b26092e6044f58c77d12744cfd7a7
Source note	uspto-grants-2014_08