HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-4-morpholinothieno[3,2-d]pyrimidine-6-carbaldehyde → HCID 86619253, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-4-morpholinothieno[3,2-d]pyrimidine-6-carbaldehyde | HCID 45789985 | — |
| Reactant | (2S)-1-methanesulfonyl-2-methylpiperazine hydrochloride | HCID 66617740 | — |
| Product | HCID 86619253 | HCID 86619253 | — |
Reaction Steps
Reaction between 2-chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidine-6-carbaldehyde and (S)-1-methanesulfonyl-2-methyl-piperazine hydrochloride salt using procedure C yielded 2-chloro-6-((S)-4-methanesulfonyl-3-methyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine. This compound was subjected to procedure A to yield the desired final compound which was purified using flash chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08802670B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-bda32e260ca4457cacf99bf883eb5495 |
| Source note | uspto-grants-2014_08 |