HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2403746Generated: November 1, 2026
2,2,2-Trifluoroethanol → 2-(2,2,2-Trifluoroethoxy)ethan-1-ol
https://huagongshe.com/reaction/2403746
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2,2,2-Trifluoroethanol | HCID 6409 | — |
| Reactant | Ethylene carbonate | HCID 7303 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | 2-(2,2,2-Trifluoroethoxy)ethan-1-ol | HCID 255854 | — |
Reaction Steps
2,2,2-trifluoroethanol (15 g), 1,3-dioxolan-2-one (19.8 g) and Et3N (15 g) were mixed together, and then the mixture was heated to 100° C. and stirred for 24 h. Then the reaction mixture was distilled to obtain intermediate BR (12.7 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08802637B2 |
|---|
| Source dataset | uspto-grants-2014_08 |
|---|
| ORD ID | ord-e75658a93d9d456795c9bc2e12918e4b |
|---|
| Source note | uspto-grants-2014_08 |
|---|
