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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2403808Generated: October 31, 2026

Phenylmethyl 3-{[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]methyl}-1-piperidinecarboxylate → 2-butoxy-8-methoxy 9-(piperidin-3-ylmethyl)-9H-purin-6-amine

https://huagongshe.com/reaction/2403808

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenylmethyl 3-{[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]methyl}-1-piperidinecarboxylateHCID 58306120—
Reactant2-(Butyloxy)-8-(methyloxy)-9-[3-(2-piperidinyl)propyl]-9H-purin-6-amineHCID 58306184—
Product2-butoxy-8-methoxy 9-(piperidin-3-ylmethyl)-9H-purin-6-amineHCID 58306241—

Reaction Steps

Prepared similarly to Intermediate 32 from phenylmethyl 3-{[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]methyl}-1-piperidinecarboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08802684B2
Source datasetuspto-grants-2014_08
ORD IDord-26bd13501b79485c9d9a06d6e132a7a8
Source noteuspto-grants-2014_08