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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2403826Generated: November 1, 2026

Iodoethane → 9-[3-(1-Ethyl-3-piperidinyl)propyl]-2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-6-amine

https://huagongshe.com/reaction/2403826

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIodoethaneHCID 6340—
Reactant9-[2-(1-Ethyl-3-piperidinyl)ethyl]-2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-6-amineHCID 58306212—
Reactant2-{[(1S)-1-Methylbutyl]oxy}-8-(methyloxy)-9-[3-(3-piperidinyl)propyl]-9H-purin-6-amineHCID 58306271—
Product9-[3-(1-Ethyl-3-piperidinyl)propyl]-2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-6-amineHCID 58306249—

Reaction Steps

Prepared similarly to Intermediate 46 from 2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9-[3-(3-piperidinyl)propyl]-9H-purin-6-amine and 2-iodoethane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08802684B2
Source datasetuspto-grants-2014_08
ORD IDord-77ee1fe4a3c44a12a4d498f44eec3fe3
Source noteuspto-grants-2014_08