Phenylmethyl 3-(5-hydroxypentyl)-1-piperidinecarboxylate → Phenylmethyl 3-(5-bromopentyl)-1-piperidinecarboxylate

HRID 2403836Notes

Reaction equation

HRID 2403836 reaction equation
[Br:1]CCCC1CCCCN1C(OCC1C=CC=CC=1)=O.O[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH:27]1[CH2:32][CH2:31][CH2:30][N:29]([C:33]([O:35][CH2:36][C:37]2[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=2)=[O:34])[CH2:28]1>>[Br:1][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH:27]1[CH2:32][CH2:31][CH2:30][N:29]([C:33]([O:35][CH2:36][C:37]2[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=2)=[O:34])[CH2:28]1

Participants

3

Reactant 2

HCID 58306078Phenylmethyl 3-(5-hydroxypentyl)-1-piperidinecarboxylateHCID 58306190Benzyl 2-(3-bromopropyl)piperidine-1-carboxylate

Product 1

HCID 58306229Phenylmethyl 3-(5-bromopentyl)-1-piperidinecarboxylate

Procedure

Prepared similarly to Intermediate 30 from phenylmethyl 3-(5-hydroxypentyl)-1-piperidinecarboxylate.

Sources & evidence

ORD record
ord-40ab677e918c4a4ba4004c309f2ca571
Source dataset
uspto-grants-2014_08
Patent number
US08802684B2

Reaction notes

Loading…