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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2403853Generated: October 31, 2026

Benzyl 4-(3-bromopropyl)piperidine-1-carboxylate → Phenylmethyl 4-{3-[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]propyl}-1-piperidinecarboxylate

https://huagongshe.com/reaction/2403853

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl 4-(3-bromopropyl)piperidine-1-carboxylateHCID 10980720—
ReactantPhenylmethyl 2-{3-[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]propyl}-1-piperidinecarboxylateHCID 58306132—
ReactantHCID 178450370HCID 178450370—
ProductPhenylmethyl 4-{3-[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]propyl}-1-piperidinecarboxylateHCID 58306243—

Reaction Steps

Prepared similarly to Intermediate 31 from 2-(butyloxy)-8-(methyloxy)-9H-purin-6-amine trifluoroacetate and phenylmethyl 4-(3-bromopropyl)-1-piperidinecarboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08802684B2
Source datasetuspto-grants-2014_08
ORD IDord-8ae2d75365d5498ba053b67dd3e11215
Source noteuspto-grants-2014_08