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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2403857Generated: November 2, 2026

Iodoethane → 9-[3-(1-Ethyl-4-piperidinyl)propyl]-2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-6-amine

https://huagongshe.com/reaction/2403857

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIodoethaneHCID 6340—
Reactant2-{[(1S)-1-Methylbutyl]oxy}-8-(methyloxy)-9-[3-(4-piperidinyl)propyl]-9H-purin-6-amineHCID 58306182—
Reactant9-[2-(1-Ethyl-3-piperidinyl)ethyl]-2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-6-amineHCID 58306212—
Product9-[3-(1-Ethyl-4-piperidinyl)propyl]-2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-6-amineHCID 58306253—

Reaction Steps

Prepared similarly to Intermediate 46 from 2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9-[3-(4-piperidinyl)propyl]-9H-purin-6-amine and 2-iodoethane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08802684B2
Source datasetuspto-grants-2014_08
ORD IDord-94df0241f3544ea89a5d38b7db0f128d
Source noteuspto-grants-2014_08