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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2403859Generated: November 1, 2026

Phenylmethyl 4-(4-bromobutyl)-1-piperidinecarboxylate → Phenylmethyl 4-{4-[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]butyl}-1-piperidinecarboxylate

https://huagongshe.com/reaction/2403859

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenylmethyl 4-(4-bromobutyl)-1-piperidinecarboxylateHCID 11046432—
ReactantPhenylmethyl 2-{3-[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]propyl}-1-piperidinecarboxylateHCID 58306132—
ReactantHCID 178450370HCID 178450370—
ProductPhenylmethyl 4-{4-[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]butyl}-1-piperidinecarboxylateHCID 58306104—

Reaction Steps

Prepared similarly to Intermediate 31 from 2-(butyloxy)-8-(methyloxy)-9H-purin-6-amine trifluoroacetate and phenylmethyl 4-(4-bromobutyl)-1-piperidinecarboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08802684B2
Source datasetuspto-grants-2014_08
ORD IDord-9e2eb254d2b3407ea3bae87fc36c7962
Source noteuspto-grants-2014_08