Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2403863Generated: October 31, 2026

Phenylmethyl 4-(4-bromobutyl)-1-piperidinecarboxylate → Phenylmethyl 4-{4-[6-amino-2-(butylamino)-8-(methyloxy)-9H-purin-9-yl]butyl}-1-piperidinecarboxylate

https://huagongshe.com/reaction/2403863

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenylmethyl 4-(4-bromobutyl)-1-piperidinecarboxylateHCID 11046432—
ReactantPhenylmethyl 2-{3-[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]propyl}-1-piperidinecarboxylateHCID 58306132—
ReactantHCID 178448879HCID 178448879—
ProductPhenylmethyl 4-{4-[6-amino-2-(butylamino)-8-(methyloxy)-9H-purin-9-yl]butyl}-1-piperidinecarboxylateHCID 58306197—

Reaction Steps

Prepared similarly to Intermediate 31 from N2-butyl-8-methoxy-9H-purine-2,6-diamine trifluoroacetic acid salt and phenylmethyl 4-(4-bromobutyl)-1-piperidinecarboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08802684B2
Source datasetuspto-grants-2014_08
ORD IDord-4f0bcc97ed5b44daba04395d9cf2cd4b
Source noteuspto-grants-2014_08