6-(4-Piperidinyl)-1-hexanol → Phenylmethyl 4-(6-hydroxyhexyl)-1-piperidinecarboxylate

HRID 2403871Notes

Reaction equation

HRID 2403871 reaction equation
OCCCCC[CH:7]1[CH2:12][CH2:11][CH2:10][N:9]([C:13]([O:15][CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[O:14])[CH2:8]1.N1CCC([CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][OH:35])CC1>>[OH:35][CH2:34][CH2:33][CH2:32][CH2:31][CH2:30][CH2:29][CH:12]1[CH2:7][CH2:8][N:9]([C:13]([O:15][CH2:16][C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=2)=[O:14])[CH2:10][CH2:11]1

Participants

3

Reactant 2

HCID 27846296-(4-Piperidinyl)-1-hexanolHCID 58306078Phenylmethyl 3-(5-hydroxypentyl)-1-piperidinecarboxylate

Product 1

HCID 58306109Phenylmethyl 4-(6-hydroxyhexyl)-1-piperidinecarboxylate

Procedure

Prepared similarly to Intermediate 64 from 6-(4-piperidinyl)-1-hexanol.

Sources & evidence

ORD record
ord-91531331eb724d978d870219b237881a
Source dataset
uspto-grants-2014_08
Patent number
US08802684B2

Reaction notes

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