Piperidine → HCID 66994670, compound

Participants

Reaction Steps

To a solution of compound G (2.3 g, 3.49 mmol) in EtOAC (50 ml) was added piperidine (0.34 mL, 3.49 mmol). The reaction mixture was stirred for 18 h at room temperature and then the solvents were removed in vacuo. The residue was dissolved in a minimum amount of EtOAc, and then was precipitated with Et2O. Precipitate was filtered off and washed with Et2O and dried to afford compound H (1.4 g, 94%). LC-MS [M+H] 437.6 (C22H36N4O5+H, calc: 437.5).

Provenance & Evidence