4-Bromo-6-methoxy-2-methylquinoline → 4-Bromo-2-methyl-quinolin-6-ol

HRID 2404159Notes

Reaction equation

HRID 2404159 reaction equation
CC1C=C(C(F)(F)F)C2C(=CC=C(O)C=2)N=1.[Br:17][C:18]1[C:27]2[C:22](=[CH:23][CH:24]=[C:25]([O:28]C)[CH:26]=2)[N:21]=[C:20]([CH3:30])[CH:19]=1>>[Br:17][C:18]1[C:27]2[C:22](=[CH:23][CH:24]=[C:25]([OH:28])[CH:26]=2)[N:21]=[C:20]([CH3:30])[CH:19]=1

Participants

3

Reactant 2

HCID 170400724-Bromo-6-methoxy-2-methylquinolineHCID 669259052-Methyl-4-trifluoromethyl-quinolin-6-ol

Product 1

HCID 669264634-Bromo-2-methyl-quinolin-6-ol

Procedure

Synthesized as per 2-Methyl-4-trifluoromethyl-quinolin-6-ol using 4-Bromo-6-methoxy-2-methyl-quinoline as starting material. ESI-MS (M+H+): 238.00/240.00.

Sources & evidence

ORD record
ord-efd216e23003476bbd0899101f5cb7a4
Source dataset
uspto-grants-2014_08
Patent number
US08802659B2

Reaction notes

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