Benzonitrile, 3-(bromomethyl)- → HCID 66677919, compound

HRID 2404304Notes

Reaction equation

HRID 2404304 reaction equation
Br[CH2:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[C:6]#[N:7].[CH3:11][NH:12][CH2:13][CH:14]([OH:17])[CH2:15][OH:16]>>[OH:17][CH:14]([CH2:15][OH:16])[CH2:13][N:12]([CH2:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[C:6]#[N:7])[CH3:11]

Participants

3

Reactant 2

HCID 97249Benzonitrile, 3-(bromomethyl)-HCID 27341223-(Methylamino)propane-1,2-diol

Product 1

HCID 66677919HCID 66677919, compound

Procedure

The title compound was prepared following the general procedure 10, starting from 3-(bromomethyl)benzonitrile and 3-(methylamino)-1,2-propanediol. It was isolated as a colorless oil (920 mg, 82%). LC/MS (Method B): 221.1 (M+H)+.

Sources & evidence

ORD record
ord-bd2122e847cb4bb7ba8ed93e036730f6
Source dataset
uspto-grants-2014_08
Patent number
US08802704B2

Reaction notes

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