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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2404338Generated: November 1, 2026

Isopropylamine → Benzonitrile, 3-(((1-methylethyl)amino)methyl)-

https://huagongshe.com/reaction/2404338

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsopropylamineHCID 6363—
ReactantBenzonitrile, 3-(bromomethyl)-HCID 97249—
ProductBenzonitrile, 3-(((1-methylethyl)amino)methyl)-HCID 485406—

Reaction Steps

The title compound was prepared following general procedure 10, starting from 3-(bromomethyl)benzonitrile and isopropyl amine. It was isolated as a yellow liquid (5.7 g, 92%). 1H NMR (DMSO-d6, 400 MHz) δ 7.73 (s, 1H), 7.67 (d, J=7.7 Hz, 1H), 7.63 (d, J=7.8 Hz, 1H), 7.49 (m, 1H), 3.56 (s, 2H), 2.75 (m, 1H), 0.83 (d, J=8.8 Hz, 6H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08802704B2
Source datasetuspto-grants-2014_08
ORD IDord-c4c28f92373848fba11a6321484e0319
Source noteuspto-grants-2014_08