HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropylamine → Benzonitrile, 3-(((1-methylethyl)amino)methyl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropylamine | HCID 6363 | — |
| Reactant | Benzonitrile, 3-(bromomethyl)- | HCID 97249 | — |
| Product | Benzonitrile, 3-(((1-methylethyl)amino)methyl)- | HCID 485406 | — |
Reaction Steps
The title compound was prepared following general procedure 10, starting from 3-(bromomethyl)benzonitrile and isopropyl amine. It was isolated as a yellow liquid (5.7 g, 92%). 1H NMR (DMSO-d6, 400 MHz) δ 7.73 (s, 1H), 7.67 (d, J=7.7 Hz, 1H), 7.63 (d, J=7.8 Hz, 1H), 7.49 (m, 1H), 3.56 (s, 2H), 2.75 (m, 1H), 0.83 (d, J=8.8 Hz, 6H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08802704B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-c4c28f92373848fba11a6321484e0319 |
| Source note | uspto-grants-2014_08 |